Uncategorized – Page 45

Ep 76: We’re upside-down?

By thelabwithbradbarton | October 25, 2017

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We’re upside-down?

In today’s rather short episode, we talk about the first creatures to have developed a centralized nervous system, though not a central nervous system as of yet. It was a simple worm like creature, with a nerve cord running along the length of its body, and an extra-large bundle of nerves toward its mouth. For worms and other invertebrate animals, like crabs, lobsters, octopuses, squid, slugs and snails, the nerve cord runs along the belly of the creature. For what would become vertebrates, including us, the main nerve cord runs along the back. Apparently, for reasons unknown, some of the worms flipped over, and decided to live their lives upside-down.

This month has included some unusually long episodes. To leave room for the upcoming Halloween special, this and the next couple of episodes are unusually short. Check back on the 31st for, “Be Afraid.: when reason can get you killed.”
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Ep 75: Electricity life and Frankensteinean experiments

By thelabwithbradbarton | October 24, 2017

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Electricity life and Frankensteinean experiments

A stun gun works by passing electricity through your muscles, causing uncontrollable contractions. An electric eel, which is actually a type of fish, can do the same thing. There is a single celled creature that can conduct electrons from hydrogen sulfide in the soil, to oxygen dissolved in the water. Almost every living cell has an electric charge. Multicellular life has found a way to use electricity to send long distance messages from one part of the organism to another. Today, we talk about electricity, life, and some slightly grotesque experiments that have been done with the relationship between the two.

Here’s an article on electric currents applied to recently deceased human body’s, that caused them to move.

1800s doctors conducted weird electrical experiments on corpse brains

Here are a couple of articles about single celled life and nanowires that they grow to conduct electricity.

Bacteria buzzing in the seabed

Biological wires carry electricity thanks to special amino acids

Here’s an article about experiments done that altered the electrical properties of cells that changed the way the organism grew. This included eyes on the tales of tadpoles, and hints of being able to regrow severed limbs in creatures that do not normally possess such a capacity.

It’s Electric: Biologists Seek to Crack Cell’s Bioelectric Code

Ep 74: side-stepping inheritance

By thelabwithbradbarton | October 20, 2017

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side-stepping inheritance

Darwin originally published “On the Origins of Species” in 1859. At the time, the mechanism of inheritance wasn’t well understood. Inheritance and the implication that lifeforms could change over time stood in contrast to the popular notion that God had created all things in perfect and unchanging forms. His theory only considered traits that come from parents, in the case of sexual reproduction, and mutation, in asexual reproduction. It turns out that organisms, especially single celled forms, can and do snag genetic information from other organisms that they aren’t related to in the least. Today we look at some of the mechanisms of horizontal gene transfer, and some examples.

Ep 73: Why go multicellular?

By thelabwithbradbarton | October 19, 2017

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Why go multicellular?

Bacteria are very successful. They’ve been around for billions of years, as compared to hundreds of millions for multicellular creatures. They have survived mass extinctions that wiped out things like the dinosaurs and others. Today, we look at salpingoeca rosetta, which can live as either a single celled creature, or in a multicellular colonial form. We compare that to the experimentally evolved multicellular colonies of yeast we introduced in the previous episode, episode 72; and examine how the multicellular creatures came about, and how and why they are no longer able to return to a single celled lifestyle.

Here’s an article about work by Nicole King, that introduced me to salpingoeca rosetta.

How Life Made the Leap From Single Cells to Multicellular Animals

Here’s an article that examines genetic ratcheting, the tendency for evolution to take steps that it cannot take back.

How Did Multicellular Life Evolve?

Ep 72: The one become many, and the many are one

By thelabwithbradbarton | October 18, 2017

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The one become many, and the many are one

How did life move from simple single celled forms, into more complex multicellular ones? In today’s episode, we talk about an experiment that induced that transition in the laboratory.

Here’s a link to an article on the experiment.

Multicellular Life Evolves in Laboratory

And here’s a link to the research paper, which happens to be freely available online.

Experimental evolution of multicellularity

Ep 71: How to make a mind—part3

By thelabwithbradbarton | October 17, 2017

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How to make a mind—part3

Take life, put it in the right environment, and give it between 3.5 and 4 billion years. We take the time to review what we’ve covered since “How to make a mind—part1,” episode 35; and “How to make a mind—part2,” episode 59. This sets us up nicely to talk about the way we evolved from simple creatures, into the oh so very complicated animals we are today.

Ep 70: Death

By thelabwithbradbarton | October 13, 2017

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Death

There are creatures that do not seem to have a natural limit on their life span. They only die when they are killed by accident or the action of sickness parasites and pathogens. Other creatures are apparently programmed to die at a given time, and under a given set of conditions. So why do we die? What is death for?

Ep 69: Sex

By thelabwithbradbarton | October 12, 2017

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Sex

This episode turned out to be both long and hard. Feel free to snicker at this point. It was long because I couldn’t resist the numerical pun. To match this episode’s number with its subject, I had to squish together the development of eukaryotes with the development of sexual reproduction. Fortunately, they may both have come about because of interactions taking place within microbial mats. It was hard because the subject turns out to be more complicated than I had thought.
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Ep 68: An environmental catastrophe

By thelabwithbradbarton | October 11, 2017

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An environmental catastrophe

Sometimes, a new species will come into being, and explode across the planet. The population increases drastically within a short time period as they learn to use new materials and new forms of energy. Sometimes, they produce material that is poisonous to forms of life that previously hadn’t encountered such substances. Many species can be pushed to the edge of extinction and beyond. This happened approximately 2.5 billion years ago, with the rise of cyanobacteria. The toxic material that was being produced was oxygen. Though it was catastrophic at the time, the presence of oxygen allowed for a new form of life, which could use the free oxygen as an energy source. This allowed for the arrival of the animals, and eventually, us.

Ep 67: Don’t let the headlines fool you. Nobody knows how life started

By thelabwithbradbarton | October 10, 2017

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Don’t let the headlines fool you. Nobody knows how life started

This is probably the least coherent episode to date. Though the precursors of life can apparently be produced by processes taking place anywhere from the deep sea to deep space, how to get from those starting chemicals to a living cell is still unknown. Rather than a lack of theories, there are just too damn many of them, all of them seemingly at least plausible, and little or no way to decide between one or another. Perhaps they all happened. Perhaps none of them. Perhaps the actual process has yet to be described. Perhaps pieces of the puzzle simply took too long, or require temperatures and pressures that cannot be reproduced in a laboratory.

Here’s a link to a Nova special on this subject that covers it much better than I have. Mind you, they had 45 minutes to do it in, rather than the 9 minutes and change I had.

Origin of Life – How Life Started on Earth